Full Professor
Strategic program(s):
Biography
Since 2001 Judith Klumperman is professor of Cell Biology and since 2008 chair of the Department of Cell Biology at the UMC Utrecht. She is also head of the Cell Microscopy Core of the UMC Utrecht, which is widely recognized as one of the best expertise centers in the world for immuno-electron microscopy. On a yearly basis the UMC Utrechts trains and assist over 40 scientists from the Netherlands and 15-20 international guests.She is often asked for expert microscopy advise and participate(d) in a large number of international collaborations.
Her research focus on understanding the molecular basis of human diseases, with an emphasis on diseases of the endo-lysosomal system. Diseases specifically addressed in my work are: Lysosomal storage disorders (Pompe disease; Mucolipidosis II/I-Cell disease) – Alzheimer disease – Hermansky Pudlak Syndrome (pigmentation bleeding disorder) - Cancer – virus and bacterial infections – ARC syndrome –Microvillar inclusion Disease. In addition, her work has elucidated fundamental concepts of endosome and lysosome biogenesis, of which the most recent finding is a novel pathway for the delivery of lysosomal membrane proteins to the lysosomes.
Research aim
We aim to comprehend the complex process of lysosome biogenesis in health and disease. Advancing our understanding holds promise for novel treatments of cancer and neurodegenerative diseases
Go to group2007: 20th Foundation lecture, Center for Cell and Molecular Biology, Hyderabad, India.
2004: VICI Award (1.25M€) from the Netherlands Organisation for Scientific Research.
1998: UMC Utrecht award: Attraction and maintenance of female talent.
Voorzitter van bestuur - Organisatie Elektronen Microscopie in Nederland - NEMI - Netherlands Electron Microscopy Infrastructure
Organisatie Elektronen Microscopie in Utrecht - Onderzoeken m.b.v. elektronen microscopie - Utrecht University, Steering Committee EM Square
Bestuurslid. - Toekomst Electronen Microscopie in Utrecht veilig stellen. - Steering Committee EM Square, UU
Geven van lezingen op congressen - Kennisoverdracht eigen onderzoeken - Diversen
Review voor wetenschappelijke tijdschriften - kennis op gebied van Celbiologie, microscopie etc. - Diversen
Als 'gaste' editor van het tijdschrift - Celbiologie - Scientific Journal 'Cell Biology'
Deelnemen aan PhD promotie commissies als voorzitter of commissielid - kennisoverdracht, niveau academici bewaken. - Nationale en internationale universiteiten
Lid van Bestuur - opleidings gerelateerd - UU IB – Institute and graduate school of Biomembranes
Board member of Biomembranes - Stimulate the Phd program - Institute of 'Biomembranes'
Grant reviewer - Voor diverse bladen (NWO, KWF, EMBO, Wellcome Trust, Medical Researh Council, KNAW, Telethon) - Grant reviewer voor diverse bladen: NWO, EMBO, KWF, Well
Reviewer for different Scientific magazines - Assess whether the articles can be published. - Science organisations in general
