Researchers Karijn Suijkerbuijk

Karijn Suijkerbuijk

Full Professor

Strategic program(s):

Biography

Karijn Suijkerbuijk is a translational medical oncologist with special interest in melanoma and immunotherapy. During her PhD, she performed research on tumor epigenetics in breast cancer in the lab of Professor Saraswati Sukumar at the Sidney Kimmel Cancer Center at Johns Hopkins University. Dr. Suijkerbuijk currently participates in multiple phase II and III clinical trials on immune checkpoint inhibitors. She published papers in Oncogene, Annals of Oncology and JNCI, received research grants from KWF and NWO and was awarded an ASCO Merit Award. Her current research focuses on clinical and immunological parameters assoaciated with immune related adverse events during checkpoint inhibition and clinicopathological factors associated with checkpoint inhibitor response.

Strategic program(s):

Contact

ksuijke2@umcutrecht.nl

Pure profile

Research groups

Molecular and cellular host-microbiota interactions

Research aim

Our research aims to unravel how the products from pathogenic and beneficial bacterial species within the intestinal microbiota contribute to human health and disease.

Go to group

Immunotherapy in solid tumors

Research aim

Our research aims at accomplishing cure and good quality of life for more and more patients with metastatic cancer by: - AI-based early identification of (non-)responders to current immunotherapy - new immunotherapies for non-responders - developing strategies to treat immunotherapy toxicity without compromising efficacy

Go to group

Recent publications

All publications

Age-Stratified Long-Term Outcomes of Immune Checkpoint Inhibitors for Stage IV Melanoma and NSCLC in The Netherlands Eline G M Steenhuis, Lieke M van Disseldorp, Femke J C Jacobs, Nathalie van Schayk, Karijn Suijkerbuijk, Marieke Louwman, Julia N S d'Hooghe, Ronald A M Damhuis, Wouter H van Geffen
Cancers, 2026, vol. 18

Discontinuation of combo immunotherapy and outcome of patients with melanoma brain metastases Mario Mandalà, Monica F Chen, Ryan J Sullivan, Maria Chiara Sergi, Michael Postow, Aleigha R Lawless, Derek Effiom, Tobias Peres, Paul C Lorigan, Patricio Serra-Bellver, Reinhard Dummer, Teresa Amaral, Marie-Lena Rasch, Diana Giannarelli, Maria Grazia Vitale, Hildur Helgadottir, Caroline Robert, Martina Ubaldi, Douglas B Johnson, Michele Del Vecchio, Alice Indini, Karijn P M Suijkerbuijk, Paul Nathan, Thomas Carter, Bart Neyns, Iris Dirven, Ines Pires da Silva, Alexander Maxwell Menzies, Lisa Zimmer, Elisabeth Livingstone, Roberta Depenni, Katharina Kähler, Axel Hauschild, Francesco Spagnolo, Anna Maria Di Giacomo, Ana Arance, Barbara Merelli, Pietro Quaglino, Ernesto Rossi, Marco Tucci, Michele Guida, Eva Muñoz-Couselo, Georgina V Long, James Larkin, Paolo A Ascierto
Journal for immunotherapy of cancer, 2026, vol. 14

ESMO Adaptation of Lines of Systemic Therapy (EnLiST) K S Saini, M Koopman, D Martins-Branco, P Bossi, S Braendegaard Winther, M Brahmi, I Braña, E Calvo, L Castelo-Branco, I Colombo, E de Azambuja, D De Ruysscher, R Dienstmann, A-M C Dingemans, M Ekholm, C Gallois, V Golfinopoulos, E Grande, S Halabi, E Le Rhun, O Le Saux, N B Leighl, S Lonardi, S Lorenzen, D Lorusso, Giuseppe Minniti, G Mountzios, J Oldenburg, S F Oosting, P Osterlund, J L Perez-Gracia, A Pellat, S Piperno-Neumann, R Plummer, C Porta, K Punie, I Ray-Coquard, J Remon, C H Ruhlmann, P Rutkowski, L L Siu, S Stacchiotti, C Suarez, K Suijkerbuijk, J Taieb, D Trapani, A Valachis, H W M van Laarhoven, A Vogel, A Zer, G Pentheroudakis, S Delaloge, C Twelves
Annals of oncology : official journal of the European Society for Medical Oncology, 2026, vol. 37, p.608-623

Neoadjuvant ipilimumab plus nivolumab in melanoma Lotte L Hoeijmakers, Petros Dimitriadis, Steven C M A Wijnen, Irene L M Reijers, Marta Lopez-Yurda, Alexander M Menzies, Annegien Broeks, Sten Cornelissen, Alejandro Torres Acosta, Anja van der Wal, Robyn P M Saw, Judith M Versluis, Winan J van Houdt, Michel W Wouters, Jurriaan Romano, Eliza A Rozeman, Lindsay G Grijpink-Ongering, Ellen Kapiteijn, Astrid A M van der Veldt, Karijn P M Suijkerbuijk, Hanna Eriksson, Geke A P Hospers, Jos A van der Hage, Dirk J Grünhagen, Arjen J Witkamp, Judith M Lijnsvelt, Willem M C Klop, Charlotte L Zuur, Annemarie Bruining, Abrahim Al-Mamgani, Thomas E Pennington, Kerwin F Shannon, Sydney Ch'ng, Andrew J Colebatch, Maria Gonzalez, Andrew J Spillane, John B A G Haanen, Robert V Rawson, Richard A Scolyer, Bart A van de Wiel, Alexander C J van Akkooi, Georgina V Long, Christian U Blank
Nature medicine, 2026, vol. 32, p.952-963

Checkpoint inhibitor effectiveness after corticosteroids and second-line immunosuppressants for immune-related adverse events in non-small-cell lung cancer E J van Dijk, M M Smeenk, F Bensch, A M Sadowksa, M V Verschueren, M Verhaert, A Llobell, Y Suzuki, D F L Liew, A Takeji, A T J Maria, B J M Peters, J S Garcia Morillo, K Chatzidionysiou, M Lidar, E C van der Hout, S Aspeslagh, G J M Herder, E M W van de Garde, L E L Hendriks, L B M Hijmering-Kappelle, W S M E Theelen, K P M Suijkerbuijk, R J Verheijden
ESMO open, 2026, vol. 11

ESMO Basic Requirements for AI-based Biomarkers In Oncology (EBAI) M Aldea, M Salto-Tellez, A Marra, R Umeton, A Stenzinger, M Koopman, A Prelaj, K L Kehl, S Gilbert, M-E Leßmann, J Lipkova, L Provenzano, F Meric-Bernstam, S Halabi, J Wu, A Pellat, K P M Suijkerbuijk, B Besse, B Ryll, C Marchió, M Crispin-Ortuzar, R Fehrmann, J Vibert, D Ferber, C Pauli, A Valachis, Federica Corso, T J Brinker, J Mateo, N Harbeck, E C Winkler, F Lopez-Rios, R Perez-Lopez, G Pentheroudakis, S Delaloge, C Benedikt Westphalen, J N Kather
Annals of oncology : official journal of the European Society for Medical Oncology, 2025, vol. 37, p.414-430

Fellowships & Awards

2007  Research year for residents (UU2007-3977) KWF
2008  Translational grant KWF (UU-2008-4217
2008  AGIKO stipend, ZonMW
2008  ASCO Merit Award

2018 ZonMW goed gebruik geneesmiddelen

External positions

lead author melanoom richtlijn - coordineren Europese melanoom richtlijn - ESMO

research funding Genmab - AI onderzoekssamenwerking in Health Holland project dat door Genmab financieel wordt ondersteund - Genmab

ESMO melanoma faculty - expertise melanoom - European Society for Medical Oncology

Lid real world data working group ESMO - onderzoek patientcohorten - European Society for Medical Oncology

Lid wetenschappelijke adviesraad - ervaring onderzoek - Maarten van der Weijden foundation

Adviesraad stichting melanoom (sinds 2019) - Vanuit expertise als melanoombehandelaar - Stichting melanoom

Lid Data Safety Monitoring Committee CHOPIN studie (vanaf 2020; studie gesponsord door BMS) - onderzoekservaring immuuntherapie - LUMC

Voorzitter wetenschappelijke commissie - Kwaliteitsverbetering en onderzoek op het gebied van melanoomzorg - Dutch Melanoma Treatment Registry (DICA)

Adviesgroep kanker in de zwangerschap - Expertise melanoom en immuuntherapie - Adviesgroep kanker in de zwangerschap

Organisatie/voorzitter jaarlijks immuno-oncologie symposium - expertise en onderzoek immuunoncologie - Immuno-oncologie symposium

Bestuurslid Tumorfocusgroep melanoom - expertise melanoom - Tumorfocusgroep melanoom

medisch expert bij melanoom nascholing en congresjournaal ASCO/ESMO - expertise melanoom - Medtalks