Profile photo Joost Frenkel

Joost Frenkel

Full Professor

Strategic program(s):


Joost Frenkel is a professor of pediatrics with a focus on family and patient centered education

He is a distinguished medical teacher with ample experience in development and provision of education to medical students residents and faculty.

He is an experienced pediatrician with a profound interest and expertise in autoinflammatory diseases.

These are disorders in which the innate inflammatory response runs out of control.

For these rare patients Frenkel leads an (inter)national clinical, genetic and research reference center.

Research has focused on the hyper IgD periodic fever syndrome due to mevalonate kinase deficiency.

International collaboration includes the Eurofever network and the international association for autoinflammatory diseases, as well as bilateral collaboration with the NIH.

Recent publications

Monitoring of Adverse Events and Safety in Autoinflammatory Diseases Yulia Vyzhga, Joost Frenkel, Antonella Insalaco, Jordi Anton, Isabelle Koné-Paut, G. Elizabeth Legger, Giovanna Fabio, Marco Cattalini, Sylvia Kamphuis, Eric Hachulla, Karoline Krause, Zelal Ekinci, Judith Sanchez-Manubens, J. Merlijn Van den Berg, Cristina Herrera Mora, Danielle Brinkman, Eztizen Labrador, Judith Potjewijd, Luca Carlini, Marta Bustaffa, Roberta Caorsi, Nicolino Ruperto, Marco Gattorno
Journal of Clinical Immunology, 2024, vol. 44, p.1-12
Unravelling the clinical heterogeneity of undefined recurrent fever over time in the European registries on Autoinflammation Y. Vyzhga, H. Wittkowski, V. Hentgen, S. Georgin-Lavialle, A. Theodoropoulou, S. Fuehner, M. Jesenak, J. Frenkel, E. Papadopoulou-Alataki, Jordi Anton, A. Nunzia Olivieri, J. Brunner, J. Sanchez, I. Koné-Paut, S. Fingerhutova, P. Pillet, U. Meinzer, R. Khubchandani, A. Jansson, J. P. Haas, R. Berendes, T. Kallinich, G. Horneff, E. Lilienthal, R. Papa, D. Foell, E. Lainka, R. Caorsi, M. Gattorno, M. Hofer
Pediatric Rheumatology, 2024, vol. 22, p.1-13
Medical Students' General Beliefs and Specific Perceptions about Patient Feedback Before and after Training in a Clinical Context M Charlotte L Eijkelboom, Renske A M de Kleijn, Joost Frenkel, Marieke F van der Schaaf
Perspectives on medical education, 2024, vol. 13, p.288-299
Games to support teaching clinical reasoning in health professions education Gilbert Koelewijn, Marije P. Hennus, Helianthe S.M. Kort, Joost Frenkel, Thijs van Houwelingen
Medical Education Online, 2024, vol. 29
Living on Site While Renovating; Flexible Instructional Design of Post-Graduate Medical Training Peter K H Deschamps, Geke M J Beugels, J Dudink, Joost Frenkel, Marije P Hennus, Marijke B Hofstra, Alexa X Rutten, Marieke Van der Schaaf
Perspectives on medical education, 2024, vol. 13, p.300-306
Isolated neurological presentations of mevalonate kinase deficiency Eva M.M. Hoytema van Konijnenburg, Esmeralda Oussoren, Joost Frenkel, Peter M. van Hasselt
JIMD Reports, 2023, vol. 64, p.53-56

Fellowships & Awards

2010: An inflammasome genome screen to detect novel disease genes in hereditary autoinflammatory disorders