Jeanine Roodhart

Full Professor

Strategic program(s):

Contact

jroodha2@umcutrecht.nl

Pure profile

Research groups

Translational oncology

Research aim

To develop, test, and implement novel therapeutic and diagnostic strategies to combat cancer by integrating fundamental and clinical research.

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Medical oncology colorectal cancer group

Research aim

To improve outcomes and quality of life for all patients with colorectal and anal cancer by developing and validating biomarkers, enhancing therapeutic strategies, refining patient selection, and studying real life treatment outcomes.

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Recent publications

All publications

A feasibility analysis to align fit-for-purpose real-world (RW) data to emulate the AZUR-1 single-arm clinical trial in patients (pts) with mismatch repair deficient (dMMR)/microsatellite instability-high (MSI-H) locally advanced rectal cancer (RC). Jeanine Roodhart, Sean O’Donnell, Linda Kalilani, Eunice Hankinson, Yichen Lu, Zoe Zeliku, Susan Boklage, Huifen Wang
Journal of Clinical Oncology, 2026, vol. 44, p.70

Portal vein embolization versus radiation lobectomy as pre-treatment for major liver resection for colorectal liver metastases Khalil Ramdhani, Rosalie C M van Rees, Daan Andel, Jeanine M L Roodhart, Arthur J A T Braat, Rutger C G Bruijnen, Inne H M Borel Rinkes, Onno Kranenburg, Marnix G E H Lam, Maarten L J Smits, Jeroen Hagendoorn
Angiogenesis, 2026, vol. 29

Accelerating personalized medicine Yasmine Abouleila, Lidwien P Smabers, Timo Voskuilen, Mayke Doorn, Roel Verkerk, Gakuro Harada, Masahiko Watanabe, Hideaki Kyan, Takahiko Kumagai, Yuichi Hikichi, René Overmeer, Jeanine M L Roodhart, Kiyotaka Matsuno, Carla S Verissimo, Sylvia F Boj
npj Biomedical Innovations, 2026, vol. 3

Safety and efficacy of lapatinib, binimetinib, and vinorelbine for RAS mutant metastatic colorectal cancer Maarten A Huismans, Eelke H Gort, Lisa T van der Heijden, Sermin M Guven Mese, Helena M Klein Wolterink, Manon N G J A Braat, Sjoerd G Elias, Filip Y F L de Vos, Lot A Devriese, Henk M W Verheul, Frans L Opdam, Miriam Koopman, Hilde H Nienhuis, Heleen A Crommelin, Hugo J G Snippert, Alwin D R Huitema, Jeanine M L Roodhart
British Journal of Cancer, 2026, vol. 134, p.1744-1753

Corrigendum to Cytosolic p120-catenin regulates growth of metastatic lobular carcinoma through Rock1-mediated anoikis resistance Ron Cj Schackmann, Miranda van Amersfoort, Judith Hi Haarhuis, Eva J Vlug, Vincentius A Halim, Jeanine Ml Roodhart, Joost S Vermaat, Emile E Voest, Petra van der Groep, Paul J van Diest, Jos Jonkers, Patrick WB Derksen
The Journal of clinical investigation, 2026, vol. 136

Circulating tumour DNA in patients with stage III colon cancer Carmen Rubio-Alarcón, Andrew Georgiadis, Ingrid A Franken, Haoyue Wang, Sietske C M W van Nassau, Suzanna J Schraa, Dave E W van der Kruijssen, Karlijn van Rooijen, Theodora C Linders, Pien Delis-van Diemen, Maartje Alkemade, Anne Bolijn, Marianne Tijssen, Margriet Lemmens, Lana Meiqari, Steven L C Ketelaars, Adria Closa-Mosquera, Miranda M W van Dongen, Mirthe Lanfermeijer, Birgit I Lissenberg-Witte, Linda J W Bosch, Teunise Bisschop-Snetselaar, Bregje C Adriaans, Amy Greer, David Riley, James R White, Christopher Greco, Liam Cox, Jesse Fox, Kaitlin Victor, Catherine Leech, Samuel V Angiuoli, Niels F M Kok, Cornelis J A Punt, Daan van den Broek, Miriam Koopman, Gerrit A Meijer, Victor E Velculescu, Jeanine M L Roodhart, Veerle M H Coupé, Mark Sausen, Geraldine R Vink, Remond J A Fijneman,
The British journal of surgery, 2026, vol. 113

External positions

Consulting Editor Framingham on Gastrointestinal Cancers - selectie meest relevante publicates ogv CRC voor publicatie als samenvatting voor vakgenoten. - framingham publishers

Board member on behalf of UMC Utrecht - lid - Hubrecht Organoid Technology

lid DSMB RADAR PANC studie - expertise als medisch oncoloog/onderzoek - UMC Utrecht

Member of the TC Bio - lid - UMC Utrecht

lid DSMB PELVEX2 studie - expertise als medisch oncoloog - Catharina Ziekenhuis

ONCODE clinical advisory board - expertise als medisch oncoloog/onderzoek - ONCODE

Clinical advisory board - adviserende rol - ONCODE

Editor patient information regarding colorectal cancer - adviseren - Kanker.nl

Steering committee - sturende rol - UPORT