Profile photo Jannie Wijnen

Jannie Wijnen

Associate Professor

Biography

The mission of my research is to use metabolic imaging in the diagnosis and treatment planning of metabolic disorders and cancer. I believe that direct measurement of tissue metabolism in the patient will lead to better understanding of the disease in the individual patient and can therefore faster translate to a change in diagnosis and consequently treatment, to better help the patient. I strive to invent and make available advanced metabolic imaging methods to aid diagnosis and treatment of the most vulnerable group of patients; children with metabolic diseases and solid tumours, who may greatly benefit from non-invasive metabolic characterisation of their disease.

 

I have a background in Biomedical Engineering and obtained my PhD in biomedicine on the topic of magnetic resonance spectroscopy (MRS) of human brain tumours at the Radboud University Nijmegen-Medical Centre. After a short post-doc position at the University Medical Centre Utrecht (UMCU) (Marina van Damma Grant), I obtained the Niels Stensen fellowship which enabled me to work as a postdoc to learn about pre-clinical research in oncology in the In-vivo Cellular and Molecular Imaging Center (ICMIC) from the department of radiology in the Johns Hopkins Medical Institutions, (Baltimore, USA) in 2011. I continued my post-doctoral research on advanced metabolic imaging methods at high magnetic field for human applications in the brain and body in the Leiden University Medical Centre and UMCU in 2012, and since 2019 as Associate Professor in the high field MR research group in the UCMU. Being part of this group, I have access to a large multidisciplinary team of experts on MRI and unique MRI equipment (7 Tesla MR system, MetaScanner). I guide and supervise master and PhD students in projects that make use of this equipment to study neurological diseases, metabolic diseases and cancer both in adults and children.

Research groups

High field MRI research group

Research aim

Our research lines incorporate inventions of MR technology to be able to see the unseen for advancing medicine. Our clinical research focus areas are cancer, dementia, cardiovascular, stroke and MSK.
Go to group

Precision imaging

Research aim

Our research lines incorporate inventions of MR technology to be able to see the unseen for advancing medicine. Our clinical research focus areas are cancer, dementia, cardiovascular, stroke and MSK.
Go to group

Perinatal neuroimaging & neuromonitoring

Research aim

We use longitudinal fetal and neonatal neuroimaging and neuromonitoring to study brain development and function, model brain diseases, and improve long term outcome in high-risk infants.
Go to group

Recent publications

A silent echo-planar spectroscopic imaging readout with high spectral bandwidth MRSI using an ultrasonic gradient axis Edwin Versteeg, Kyung Min Nam, Dennis W.J. Klomp, Alex A. Bhogal, Jeroen C.W. Siero, Jannie P. Wijnen
Magnetic Resonance in Medicine, 2024, vol. 91, p.2247-2256
Amide proton transfer weighted imaging in pediatric neuro-oncology Iris V. Obdeijn, Evita C. Wiegers, Lejla Alic, Sabine L.A. Plasschaert, Mariëtte E.G. Kranendonk, Hans M. Hoogduin, Dennis W.J. Klomp, Jannie P. Wijnen, Maarten H. Lequin
NMR in Biomedicine, 2024, vol. 37
Improving advanced intraoperative MRI methods during pediatric neurosurgery Pien E.J. Jellema, Lilli M. Mannsdörfer, Fredy Visser, Alberto De Luca, Cynthia L.E. Smit, Eelco W. Hoving, Kirsten M. van Baarsen, Thomas Lindner, Henk Jan M.M. Mutsaerts, Jan Willem Dankbaar, Maarten H. Lequin, Jannie P. Wijnen
NMR in Biomedicine, 2024, vol. 37
Finding joy, creativity and meaning through unusual interdisciplinary collaborations J. Duncan, S. Knittel, S. Hofmann, F. Albronda, D. Lakens, J. P. Wijnen, M. D. Veldhuizen, D. Tetteroo, C. Schoevaars, M. Boes, S. Brugman, C. Lamain,
Humanities and Social Sciences Communications, 2024, vol. 11
Advanced intraoperative MRI in pediatric brain tumor surgery Pien E J Jellema, Jannie P Wijnen, Alberto De Luca, Henk J M M Mutsaerts, Iris V Obdeijn, Kirsten M van Baarsen, Maarten H Lequin, Eelco W Hoving
Frontiers in Physiology, 2023, vol. 14
Will standardization kill innovation? Jannie P. Wijnen, Nicole Seiberlich, Xavier Golay
Magnetic Resonance Materials in Physics, Biology and Medicine, 2023, vol. 36, p.525-528

Fellowships & Awards

2020: VIDI Silent MRI with the speed of CT and richer metabolic information than PET

2014: Saving breast cancer patients from ineffective cytotoxic treatment.

2013: VENI Towards non-invase metabolic imaging of breast cancer staging at 7 Tesla to guide treatments.

2010: Marina van Damme grant

2010: Monitoring of response to breast cancer therapy by 31P Magnetic Resonance Spectroscopy