Jan Erik Freund

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Research groups

Pathology of gastrointestinal tract tumors

Research aim

Our aim is to increase understanding of the pathogenesis of gastrointestinal tract tumors and to identify and validate potential histopathological and molecular biomarkers to improve and personalize therapy for patients.

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Recent publications

Association between effectiveness of treatment with curative intent and outcomes of first-line systemic therapy in metachronous metastatic gastroesophageal adenocarcinoma D Kamp, A M May, M J M van Velzen, S Mook, J E Freund, B Mostert, R H A Verhoeven, H W M van Laarhoven, N Haj Mohammad
British Journal of Cancer, 2026, vol. 134, p.1420-1428
The amount of mediastinal lymph nodes dissected in robot-assisted cervical esophagectomy—an experimental cadaver study Romy C. van Jaarsveld, Peter P. Grimminger, Jan Erik Freund, Teus J. Weijs, Lodewijk A.A. Brosens, Sylvia van der Horst, Ronald L.A.W. Bleys, Jelle P. Ruurda, Richard van Hillegersberg
Journal of Thoracic Disease, 2025, vol. 17, p.10748-10757
Head-to-head comparison of two artificial intelligence tools for detecting lymph-node metastases in whole slide pathology images within and beyond their intended use Rachel N Flach, Milan Samuels, Natalie D Ter Hoeve, Nikolas Stathonikos, Trudy G N Jonges, Jan Erik Freund, Gerben E Breimer, Willeke A M Blokx, Frans Schutgens, Tri Q Nguyen, Paul J van Diest, Carmen van Dooijeweert
Modern Pathology, 2025, vol. 38
Impact of endoscopic ultrasonography with fine needle aspiration assessing clinical lymph node staging on radiotherapy treatment planning in esophageal cancer patients R B den Boer, M E Sanders, G J Meijer, N Haj Mohammad, M A M T Verhagen, J E Freund, L A A Brosens, B L A M Weusten, P Friederich, L Alvarez Herrero, J P Ruurda, R van Hillegersberg, S Mook
Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 2025, vol. 38
Implementing robot-assisted minimally invasive gastrectomy (RAMIG) for gastric cancer in a European tertiary referral center Lianne Triemstra, Cas de Jongh, Hylke J F Brenkman, Bas L A M Weusten, Jan Erik Freund, Richard van Hillegersberg, Jelle P Ruurda
European Journal of Surgical Oncology, 2025, vol. 51
Outcomes of CEM43 in Predicting Thermal Damage Induced by Focal Laser Ablation in Controlled Ex Vivo Experiments K C C de Bie, R A A van Kollenburg, L A M J G van Riel, M Almasian, J E Freund, P R Bloemen, R Zweije, J Crezee, B F Coolen, G J Strijkers, T M de Reijke, J R Oddens, A G J M van Leeuwen, D M de Bruin
Lasers in Surgery and Medicine, 2024, vol. 56, p.723-733

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