Profile photo Jaap Kappelle

Jaap Kappelle

Full Professor

Strategic program(s):

Biography

Jaap Kappelle was registered as a clinical neurologist in 1988. He obtained his PhD degree in Utrecht (1990) with Jan van Gijn. He carried out postdoctoral research at the University of Iowa, Iowa City, USA (1991) and the John P. Robarts Research Institute, London (Ontario) Canada (1998). He was appointed assistant professor at the University Utrecht in 1988, associate professor in 1994 and full professor in 2000.  He is former head of the department of cerebrovascular diseases of the University Medical Centre (UMC) Utrecht (2011-2020). As of 2020 he has been appointed medicale safety officer of the UMCU.

His research is embedded in the research lines 'Circulatory Health' and 'Brain' of the UMCU in close collaboration with the departments of neurosurgery, radiology, vascular medicine, vascular surgery, rehabilitation, clinical epidemiology, primary health care and neuropsychology. His current line of research concerns stroke, in particular the diagnosis, treatment and prognosis of patients with TIA or ischaemic stroke. As part of his research activities he is member of steering committees of reserrch programs embedded in 'Cardio-Vasculair Onderzoek Nederland' and serves as expert adjucation panelmeber of several clinical trials.

He is founding president of the Dutch Neurovascular Society. He is a member of the education committee if the Dutch Neurological Society and Dutch delegate for stroke of the European Association of Neurology. Besides his regular education duties in the UMC Utrecht, he is member of the board of supervisors of the Medical student Societÿ 'MSFU SAMS)

Jaap Kappelle is member elect of the European Stroke Council, the World Stroke Organisation and premium professional silver heart memeber  of the American Heart Associatiuon. He holds also memberships of the Dutch Society of Neurology, the Dutch Vascular Society, the European Association of Neurology, the Royal Dutch Association of Medicine and the Dutch Society of Medical Litigation Assessments.

He serves as neutral expert for different courts, insurance companies and health care organisations. 

Research line

Cerebrovascular diseases

publications

https://pubmed.ncbi.nlm.nih.gov/?term=Kappelle+LJ&sort=pubdate

https://pubmed.ncbi.nlm.nih.gov/?term=Kapelle+LJ&sort=pubdate

https://pubmed.ncbi.nlm.nih.gov/?term=Kappelle+J&sort=pubdate

Strategic program(s):

Contact

Recent publications

Dynamic PET imaging in patients with unilateral carotid occlusion shows lateralized cerebral hypoperfusion, but no amyloid binding Naomi Lp Starmans, Anna E Leeuwis, Edwin Bennink, Sebastiaan L Meyer Viol, Sandeep Sv Golla, Jan Willem Dankbaar, Esther E Bron, Geert Jan Biessels, L Jaap Kappelle, Wiesje M van der Flier, Nelleke Tolboom,
Journal of Alzheimer's disease : JAD, 2025, vol. 105, p.519-530
Sex-Based Analysis of Treatment, Time Metrics, and Outcomes in Acute Ischemic Stroke Patients Treated in the Netherlands Lieza Geertje Exalto, Mariam Ali, Lotte J Stolze, M Irem Baharoglu, Marieke J H Wermer, L Jaap Kappelle,
Cerebrovascular diseases (Basel, Switzerland), 2024, vol. 54, p.356–362
Prediction of Severe Baseline Asymptomatic Carotid Stenosis and Subsequent Risk of Stroke and Cardiovascular Disease Michiel H.F. Poorthuis, Steven H.J. Hageman, Aernoud T.L. Fiolet, L. Jaap Kappelle, Michiel L. Bots, Ph Gabriel Steg, Frank L.J. Visseren, Deepak L. Bhatt, Gert J. De Borst
Stroke, 2024, vol. 55, p.2632-2640
Sex differences in cognitive functioning in patients with heart failure Sanne Kuipers, L Jaap Kappelle, Jacoba P Greving, Raquel P Amier, Jeroen de Bresser, Esther E Bron, Anna E Leeuwis, Nick Marcks, Hester M den Ruijter, Geert Jan Biessels, Lieza G Exalto,
International Journal of Cardiology, 2024, vol. 418
Decompressive craniectomy plus best medical treatment versus best medical treatment alone for spontaneous severe deep supratentorial intracerebral haemorrhage Jürgen Beck, Christian Fung, Daniel Strbian, Lukas Bütikofer, Werner J. Z'Graggen, Matthias F. Lang, Seraina Beyeler, Jan Gralla, Florian Ringel, Karl Schaller, Nikolaus Plesnila, Marcel Arnold, Werner Hacke, Peter Jüni, Alexander David Mendelow, Christian Stapf, Rustam Al-Shahi Salman, Jenny Bressan, Stefanie Lerch, Arsany Hakim, Nicolas Martinez-Majander, Anna Piippo-Karjalainen, Peter Vajkoczy, Stefan Wolf, Gerrit A. Schubert, Anke Höllig, Michael Veldeman, Roland Roelz, Andreas Gruber, Philip Rauch, Dorothee Mielke, Veit Rohde, Thomas Kerz, Eberhard Uhl, Enea Thanasi, Hagen B. Huttner, Bernd Kallmünzer, L. Jaap Kappelle, Wolfgang Deinsberger, Christian Roth, Robin Lemmens, Jan Leppert, Jose L. Sanmillan, Jonathan M. Coutinho, Katharina A.M. Hackenberg, Gernot Reimann, Mikael Mazighi, Claudio L.A. Bassetti, Heinrich P. Mattle, Andreas Raabe,
The Lancet, 2024, vol. 403, p.2395-2404
Henry J.M. Barnett (1922–2016) J. van Gijn, L. J. Kappelle
Journal of Neurology, 2024, vol. 271, p.7057-7058

External positions

beoordeling casuïstiek op neurologisch gebied - zie boven - Neuro Orthopedisch Centrum