De novo H3.3K27M-altered diffuse midline glioma in human brainstem organoids to dissect GD2 CAR T cell function
Nils Bessler, Amber K.L. Wezenaar, Hendrikus C.R. Ariese, Celina Honhoff, Noëlle Dommann, Ellen J. Wehrens, Cristian Ruiz Moreno, Thijs J.M. van den Broek, Raphaël V.U. Collot, Daan J. Kloosterman, Farid Keramati, Mieke Roosen, Sam de Blank, Esmée van Vliet, Mario Barrera Román, Lucrezia C.D.E. Gatti, Ali Ertürk, Jürgen Kuball, Zsolt Sebestyén, Marcel Kool, Sara Patrizi, Evelina Miele, Annette Künkele, Mariëtte E.G. Kranendonk, Annelisa M. Cornel, Stefan Nierkens, Christian Mayer, Hendrik G. Stunnenberg, Anna Alemany, Maria Alieva, Anne C. Rios
Nature Cancer, 2026, vol. 7, p.316–333
A longitudinal single-cell atlas to predict outcome and toxicity after BCMA-directed CAR T cell therapy in multiple myeloma
Michael Rade, David Fandrei, Markus Kreuz, Sabine Seiffert, Anja Grahnert, Maik Friedrich, Thomas Wiemers, Patrick Born, Luise Fischer, Heike Weidner, Lorenz C. Hofbauer, Ronny Baber, Song Yau Wang, Enrica Bach, Sandra Hoffmann, Jonathan Scolnick, Mirco Friedrich, Farid Keramati, Peter Brazda, Zsolt Sebestyen, Jürgen Kuball, Miriam Alb, Lukas Scheller, Michael Hudecek, Hermann Einsele, Klaus H. Metzeler, Marco Herling, Carmen Diana Herling, Madlen Jentzsch, Georg Nikolaus Franke, Andreas Boldt, Ulrike Köhl, Uwe Platzbecker, Vladan Vucinic, Kristin Reiche, Maximilian Merz
Cancer Cell, 2025, vol. 44, p.586-603.e9
Systemic inflammation impairs myelopoiesis and interferon type I responses in humans
Farid Keramati, Guus P Leijte, Niklas Bruse, Inge Grondman, Ehsan Habibi, Cristian Ruiz-Moreno, Wout Megchelenbrink, Annemieke M Peters van Ton, Hidde Heesakkers, Manita E Bremmers, Erinke van Grinsven, Kiki Tesselaar, Selma van Staveren, Walter J van der Velden, Frank W Preijers, Brigit Te Pas, Raoul van de Loop, Jelle Gerretsen, Mihai G Netea, Hendrik G Stunnenberg, Peter Pickkers, Matthijs Kox
Nature immunology, 2025, vol. 26, p.737–747
Mapping T cell dynamics to molecular profiles through behavior-guided transcriptomics
A K L Wezenaar, U Pandey, F Keramati, M Hernandez-Roca, P Brazda, M Barrera Román, A Cleven, F Karaiskaki, Tineke Aarts-Riemens, S de Blank, P Hernandez-Lopez, S Heijhuurs, A Alemany, J Kuball, Z Sebestyen, J F Dekkers, H G Stunnenberg, M Alieva, A C Rios
Nature protocols, 2025, vol. 20, p.2453-2480
