Eva van Rooij

Full Professor

Strategic program(s):

Contact

erooij@umcutrecht.nl

Pure profile

Research groups

Inherited heart disease (cardiogenetics)

Research aim

We aim to enhance patient and family lives impacted by inherited cardiomyopathies. Our efforts target gene and variant identification, disease mechanisms, factors influencing disease outcomes, therapy optimization, and exploration of novel therapies.

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Cardiac repair and regeneration

Research aim

Current available therapies for chronic heart diseases only alleviate symptoms and prevent the disease from becoming worse. We aim to improve our understanding and stimulate our natural potential for myocardial repair.

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Molecular science & therapy in heart failure

Research aim

Current available therapies for chronic heart diseases only alleviate symptoms and prevent the disease from becoming worse. We aim to improve our understanding of heart failure and develop new strategies for therapy.

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Recent publications

All publications

PKP2 orchestrates OXPHOS expression in cardiomyocytes via a PGC1α-dependent mechanism Su Ji Han, Daphne van den Berg, Hesther de Ruiter, Hoyee Tsui, Eirini Kyriakopoulou, Tim Koopmans, Ilaria Perini, Jantine Monshouwer-Kloots, Sebastiaan J van Kampen, Anneline S J M Te Riele, Ilse R Kelters, Monica Gianoli, Boudewijn M T Burgering, Eva van Rooij
Cardiovascular research, 2026, vol. 122, p.2024-2038

RRAGD p.(Ser76Leu) Variant Causes Dysregulated Expression of Muscle Development and Cytoskeleton Genes in Cardiomyocytes Anastasia Adella, Sara B van Katwijk, Pieter A Leermakers, Willem B van Ham, Hesther de Ruiter, Judita Ilgutytė, Suzanne Hendrickx, Levi Nijland, Teun P de Boer, Eva van Rooij, Joost G J Hoenderop, Jeroen H F de Baaij
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2026, vol. 40

Repressive chromatin regulates fibrotic potential through Suv39h1 in the heart Tim Koopmans, Eva van Rooij
Cardiovascular research, 2026, vol. 122, p.805–807

Maintaining the LYVE1 line through macrophage and lymphatic interplay in the regenerating neonatal heart Tim Koopmans, Eva van Rooij
Nature Cardiovascular Research, 2025, vol. 4, p.1211-1213

Cardiomyocyte SORBS2 expression increases in heart failure and regulates integrin interactions and extracellular matrix composition Louk T. Timmer, Elvira den Hertog, Danielle Versteeg, Harm Post, Job A.J. Verdonschot, Jantine Monshouwer-Kloots, Eirini Kyriakopoulou, Ilaria Perini, Tim Koopmans, Petra van der Kraak, Lorena Zentilin, Stephane R.B. Heymans, Aryan Vink, Mauro Giacca, Albert J.R. Heck, Eva van Rooij
Cardiovascular research, 2025, vol. 121, p.585-600

Molecular gatekeepers of endogenous adult mammalian cardiomyocyte proliferation Tim Koopmans, Eva van Rooij
Nature Reviews Cardiology, 2025, vol. 22, p.857-882