Dominique de Kleijn

Full Professor

Strategic program(s):

Research groups

Therapy of atherosclerosis and aneurysms

Research aim

Development and validation of image guided interventions, medical devices and pharmaceutical interventions (eg anti-inflammatory/coagulation) to improve outcome of atherosclerotic disease and aneurysms

Go to group

Recent publications

Atherosclerotic Plaque Epigenetic Age Acceleration Predicts a Poor Prognosis and Is Associated With Endothelial-to-Mesenchymal Transition in Humans Ernest Diez Benavente, Robin J G Hartman, Tim R Sakkers, Marian Wesseling, Yannicke Sloots, Lotte Slenders, Arjan Boltjes, Barend M Mol, Gert J de Borst, Dominique P V de Kleijn, Koen H M Prange, Menno P J de Winther, Johan Kuiper, Mete Civelek, Sander W van der Laan, Steve Horvath, Charlotte Onland-Moret, Michal Mokry, Gerard Pasterkamp, Hester M den Ruijter
Arteriosclerosis, Thrombosis, and Vascular Biology, 2024, vol. 44, p.1419-1431
Diacylglycerols and Lysophosphatidic Acid, Enriched on Lipoprotein(a), Contribute to Monocyte Inflammation Kim E. Dzobo, Arjen J. Cupido, Barend M. Mol, Lotte C.A. Stiekema, Miranda Versloot, Maaike Winkelmeijer, Jorge Peter, Anne Marije Pennekamp, Stefan R. Havik, Frédéric M. Vaz, Michel Van Weeghel, Koen H.M. Prange, Johannes H.M. Levels, Menno P.J. De Winther, Sotirios Tsimikas, Albert K. Groen, Erik S.G. Stroes, Dominique P.V. De Kleijn, Jeffrey Kroon
Arteriosclerosis, Thrombosis, and Vascular Biology, 2024, vol. 44, p.720-740
Blood biomarkers for the differentiation between central and peripheral vertigo in the emergency department Vincent W Klokman, Fiona N Koningstein, Job W W Dors, Marieke S Sanders, Sam W Koning, Dominique P V de Kleijn, Kim E Jie
Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2024, vol. 31, p.371-385
Predictors of bleeding complications during catHeter-dirEcted thrombolysis for peripheral arterial occlusions (POCHET) Barend M. Mol, Maarten C. Verwer, Rob Fijnheer, Jasper Florie, Oscar A. Groot, Falco Hietbrink, Mathilde Nijkeuter, Evert Jan P.A. Vonken, Vincent van Weel, Dominique P.V. de Kleijn, Gert J. de Borst,
PLoS ONE, 2024, vol. 19
Predictors of major adverse cardiac events among patients with chest pain and low HEART score in the emergency department Andrew Fu Wah Ho, Chun En Yau, Jamie Sin Ying Ho, Swee Han Lim, Irwani Ibrahim, Win Sen Kuan, Shirley Beng Suat Ooi, Mark Y. Chan, Ching Hui Sia, Arend Mosterd, Crystel M. Gijsberts, Vince C. de Hoog, Ingrid E.M. Bank, Pieter A. Doevendans, Dominique P.V. de Kleijn
International Journal of Cardiology, 2024, vol. 395
The accumulation of erythrocytes quantified and visualized by Glycophorin C in carotid atherosclerotic plaque reflects intraplaque hemorrhage and pre-procedural neurological symptoms Joost M Mekke, Tim R Sakkers, Maarten C Verwer, Noortje A M van den Dungen, Yipei Song, Clint L Miller, Aloke V Finn, Gerard Pasterkamp, Michal Mokry, Hester M den Ruijter, Aryan Vink, Dominique P V de Kleijn, Gert J de Borst, Saskia Haitjema, Sander W van der Laan
Scientific Reports, 2023, vol. 13

External positions

CSO/consultant, Persuasive BV

Advisory board, Ilias Biologics

Coordinator Large animal research, University Medical Center Utrecht

Local organisor and chairman Extracellular Vesicle Meetings Selectbio, Selectbio