Dominique de Kleijn

Full Professor

Strategic program(s):

Contact

dkleijn@umcutrecht.nl

Pure profile

Research groups

Therapy of atherosclerosis and aneurysms

Research aim

Development and validation of image guided interventions, medical devices and pharmaceutical interventions (eg anti-inflammatory/coagulation) to improve outcome of atherosclerotic disease and aneurysms

Go to group

Recent publications

All publications

Female-Biased VSMC GRNs Predict MYH9 as Regulator of Fibrous Plaque Phenotype R Noah Perry, Graham Lenert, Ernest Diez Benavente, Aydin Bölük, Rebecca Hernandez, Lijiang Ma, Nicolas Barbera, Kelsey Watts, Victor Mendoza, Tiit Örd, Mari Taipale, Nadja Sachs, Jessica Pauli, Michal Mokry, Dominique P V de Kleijn, Menno P J de Winther, Manuel Mayr, Lars Maegdefessel, Karen Reue, Minna U Kaikkonen, Johan L M Björkegren, Hester M den Ruijter, Mete Civelek
Circulation research, 2026, vol. 138

Genetically determined ancestry associates with morphological and molecular carotid plaque features Nima Fahim, Tim R. Sakkers, Floor B.H. van der Zalm, Joost Hoekstra, Dominique P.V. de Kleijn, Michal Mokry, Jose Verdezoto Mosquera, Gerard Pasterkamp, Hester M. den Ruijter, Clint L. Miller, Jessica van Setten, Sander W. van der Laan
Atherosclerosis, 2026, vol. 415

Atherosclerotic Fibrous Plaques in Women Present ECM Remodeling Linked to TGF-β Tim R Sakkers, Eloi Mili, Hanna Winter, Daniek Kapteijn, R Noah Perry, Nicolas Barbera, Kelsey Watts, Inês R Dias, Denitsa Meteva, Marian Wesseling, Barend M Mol, Gert J de Borst, Dominique P V de Kleijn, Sander W van der Laan, Mete Civelek, Stephen J White, Lars Maegdefessel, Manuel Mayr, Gerard Pasterkamp, Michal Mokry, Ernest Diez Benavente, Hester M den Ruijter
Circulation research, 2026, vol. 138

Major depression and atherosclerotic disease Emma Pruin, Meike Bartels, Ernest Diez Benavente, Noortje A M van den Dungen, Joost K R Hoekstra, Dominique D P de Kleijn, Lennart P L Landsmeer, Michal Mokry, Gerard Pasterkamp, Brenda W J H Penninx, Wouter J Peyrot, Hester M den Ruijter, Sander W van der Laan, Yuri Milaneschi
European Neuropsychopharmacology, 2026, vol. 106

Integrating multi-modal omics to identify therapeutic atherosclerosis pathways for coronary heart disease Sophie C. de Ruiter, Marion van Vugt, Chris Finan, Diederick E. Grobbee, Dominique P.V. de Kleijn, Gerard Pasterkamp, Hester M. den Ruijter, Ernest Diez Benavente, Sanne A.E. Peters, A. Floriaan Schmidt
EBioMedicine, 2025, vol. 121

Carotid Plaques Show More Unstable Characteristics Between 2010 and 2021 After a Prior Decade of Stabilization Barend M. Mol, Tetiana Motsak, Joost K.R. Hoekstra, Gerard Pasterkamp, Gert J. de Borst, Dominique P.V. de Kleijn
Journal of the American Heart Association, 2025, vol. 14