Bas Oldenburg

Full Professor

Strategic program(s):

Contact

boldenbu@umcutrecht.nl

Pure profile

Research groups

Inflammatory bowel diseases

Research aim

Our research is focused on the elucidation of the pathogenesis of Inflammatory bowel diseases (IBD), personalized medicine and on a severe complication of IBD: colitis-associated colorectal carcinoma.

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Molecular and cellular host-microbiota interactions

Research aim

Our research aims to unravel how the products from pathogenic and beneficial bacterial species within the intestinal microbiota contribute to human health and disease.

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Tissue immunology

Research aim

Our mission is to comprehensively understand, monitor, and target immune-mediated inflammatory diseases such as IBD, AD and systemic autoimmune diseases. We aim to unravel (tissue) immune dysregulation and induce long-lasting disease modification.

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Recent publications

All publications

Clonal overlap and convergent clustering of T cell receptor signatures in Crohn's disease in monozygotic twins Eelco C Brand, Romi Vandoren, Lisanne Lutter, Vincent M L Van Deuren, Nila H Servaas, Aridaman Pandit, Pieter Meysman, Bas Oldenburg, Femke van Wijk,
Inflammatory bowel diseases, 2026, vol. 32, p.1561–1575

Prospective real-world experience with risankizumab in difficult-to-treat Crohn's disease Loriane M M Verleye, Marieke J Pierik, Annemarie C de Vries, Fiona D M van Schaik, Andrea E van der Meulen-de Jong, Willemijn A van Dop, Mark Löwenberg, Marijn C Visschedijk, Myrthe R Naber, Dianne G Bouwknegt, Tessa E H Römkens, Alexander G L Bodelier, Philip W Voorneveld, Bas Oldenburg, Lauranne A A P Derikx, Marjolijn Duijvestein, Zlatan Mujagić,
Inflammatory bowel diseases, 2026, vol. 32, p.1460-1470

Univariate- and machine learning-based plasma metabolite signature differentiates PSC-IBD from IBD and is predicted to be driven by gut microbial changes Joanna C Wolthuis, Johannes P D Schultheiss, Stefanía Magnúsdóttir, Edwin Stigter, Yuen Fung Tang, Judith Jans, Bas Oldenburg, Jeroen de Ridder, Saskia van Mil
Metabolomics, 2026, vol. 22

Blood and tissue correlates of steroid non-response in checkpoint inhibition-induced immune-related adverse events Mick J M van Eijs, M Marlot van der Wal, Hedi-Britt Klotškova, Noël M M Dautzenberg, Mark Schuiveling, Rik J Verheijden, Fiona D M van Schaik, Bas Oldenburg, Stefan Nierkens, Karijn P M Suijkerbuijk, Femke van Wijk,
Communications medicine, 2025, vol. 5, p.1-14

Mucosal Kinase Activity and Inflammatory Profiles in Inflammatory Bowel Disease, and in Relation with Tofacitinib Response Eelco C Brand, Britt Roosenboom, Lisanne Lutter, Bea Malvar Fernandez, Savithri Rangarajan, Elly Van Koolwijk, Sara Van Gennep, Geert R D'Haens, Ellen G Van Lochem, Carmen S Horjus Talabur Horje, Kris A Reedquist, Femke Van Wijk, Bas Oldenburg
Journal of Crohn's & Colitis, 2025, vol. 19

Food Compounds Associated With Disease Activity in Inflammatory Bowel Disease Marie Meima, Joost Westerhout, Marjolein Meijerink, Sabina Bijlsma, Fiona van Schaik, Bas Oldenburg, Geert Houben
Inflammatory bowel diseases, 2025, vol. 31, p.3051-3059