Profile photo André Knulst

André Knulst

Full Professor

Strategic program(s):


Prof. dr. André C. Knulst is dermatologist and immunologist at the Department of Dermatology/Allergology of the UMC Utrecht. He heads the outpatient department of Allergology and  has a longstanding experience in diagnosis and treatment of patients with allergies, urticaria and angio-edema, with a particular interest in food allergy, urticaria and angio-edema. The Dept. of Dermatology/Allergology is a centre of expertise for eczema, food allergy and urticaria/angio-edema. Prof. Knulst is involved in the training of dermatologists, otolaryngologists, pediatric allergists, and clinical immunologists/internist-allergologists.

He also heads the allergy research. Within the UMC Utrecht there is a close collaboration with the department of Children’s Pulmonology and Allergology and the Center of Translational Immunology of the UMC Utrecht. His research focus is on patient profiling and improvement of food allergy diagnosis a.o. using component resolved diagnostics. He participated in many multicenter studies a.o. the EU sponsored SAFE, CREATE and Europrevall projects. Another research area of particular interest is the development of novel therapeutic options for food allergy. He was involved in the VIPES study on the efficacy and safety of epicutaneously administered peanut and the FAST study on the efficacy of subcutaneous immunotherapy using a hypoallergenic cod fish parvalbumin.


Research groups

Acute inflammation - Food allergy

Research aim

We aim to improve allergy diagnosis and increase quality of life to reduce healthcare costs by developing predictive diagnostic tools, get insight into food allergy mechanisms and increase understanding and awareness of allergic risks of (new) foods.
Go to group

Acute inflammation – Chronic urticaria and idiopathic angio-edema

Research aim

To improve diagnostics and treatment for patients with chronic urticaria, increase quality of life and reduce healthcare costs. To clarify pathomechanism of CU as well as response to different therapeutic strategies and its predictors.
Go to group

Recent publications

House dust mite sublingual allergen immunotherapy tablet is safe and well-tolerated in Dutch clinical practice Žana Tempels-Pavlica, Mark C J Aarts, Paco M J Welsing, Akke-Nynke van der Meer, Leonard P van der Zwan, Elena Uss, André C Knulst
Frontiers in allergy, 2024, vol. 5
EAACI Molecular Allergology User's Guide 2.0 Stephanie Dramburg, Christiane Hilger, Alexandra F Santos, Leticia de Las Vecillas, Rob C Aalberse, Nathalie Acevedo, Lorenz Aglas, Friedrich Altmann, Karla L Arruda, Riccardo Asero, Barbara Ballmer-Weber, Domingo Barber, Kirsten Beyer, Tilo Biedermann, Maria Beatrice Bilo, Simon Blank, Philipp P Bosshard, Heimo Breiteneder, Helen A Brough, Merima Bublin, Dianne Campbell, Luis Caraballo, Jean Christoph Caubet, Giorgio Celi, Martin D Chapman, Maksymilian Chruszcz, Adnan Custovic, Rebecca Czolk, Janet Davies, Nikolaos Douladiris, Bernadette Eberlein, Motohiro Ebisawa, Anna Ehlers, Philippe Eigenmann, Gabriele Gadermaier, Mattia Giovannini, Francisca Gomez, Rebecca Grohman, Carole Guillet, Christine Hafner, Robert G Hamilton, Michael Hauser, Thomas Hawranek, Hans Jürgen Hoffmann, Thomas Holzhauser, Tomona Iizuka, Alain Jacquet, Thilo Jakob, Bente Janssen-Weets, Uta Jappe, Marek Jutel, Tanja Kalic, Sandip Kamath, Sabine Kespohl, Jörg Kleine-Tebbe, Edward Knol, André Knulst, Jon R Konradsen, Peter Korošec, Annette Kuehn, Gideon Lack, Thuy-My Le, Andreas Lopata, Olga Luengo, Mika Mäkelä, Alessandro Maria Marra, Clare Mills, Martine Morisset, Antonella Muraro, Anna Nowak-Wegrzyn, Roni Nugraha, Markus Ollert, Kati Palosuo, Elide Anna Pastorello, Sarita Ulhas Patil, Thomas Platts-Mills, Anna Pomés, Pascal Poncet, Ekaterina Potapova, Lars K Poulsen, Christian Radauer, Suzana Radulovic, Monika Raulf, Pierre Rougé, Joaquin Sastre, Sakura Sato, Enrico Scala, Johannes M Schmid, Peter Schmid-Grendelmeier, Denise Schrama, Hélène Sénéchal, Claudia Traidl-Hoffmann, Marcela Valverde-Monge, Marianne van Hage, Ronald van Ree, Kitty Verhoeckx, Stefan Vieths, Magnus Wickman, Josefina Zakzuk, Paolo M Matricardi, Karin Hoffmann-Sommergruber
Pediatric Allergy and Immunology, 2023, vol. 34
Co-sensitization between legumes is frequently seen, but variable and not always clinically relevant Mark Smits, Kitty Verhoeckx, André Knulst, Paco Welsing, Aard de Jong, Marco Gaspari, Anna Ehlers, Paulien Verhoeff, Geert Houben, Thuy My Le
Frontiers in allergy, 2023, vol. 4
Accidental allergic reactions to food in adolescents and adults Astrid Versluis, Thuy-My Le, Geert F Houben, André C Knulst, Harmieke Van Os-Medendorp
Frontiers in allergy, 2023, vol. 4
A European-Japanese study on peach allergy E. J.J. Kallen, A. Revers, M. Fernández-Rivas, R. Asero, B. Ballmer-Weber, L. Barreales, S. Belohlavkova, F. de Blay, M. Clausen, R. Dubakiene, M. Ebisawa, C. Fernández-Perez, P. Fritsche, Y. Fukutomi, D. Gislason, K. Hoffmann-Sommergruber, M. Jedrzejczak-Czechowicz, A. C. Knulst, M. L. Kowalski, T. Kralimarkova, J. Lidholm, C. Metzler, E. N.C. Mills, N. G. Papadopoulos, T. A. Popov, A. Purohit, I. Reig, S. L. Seneviratne, A. Sinaniotis, M. Takei, S. A. Versteeg, A. E. Vassilopoulou, S. Vieths, P. M.J. Welsing, A. H. Zwinderman, T. M. Le, R. Van Ree
Allergy: European Journal of Allergy and Clinical Immunology, 2023, vol. 78, p.2497-2509
Component Ana o 3 versus extract for cashew nut allergy Emily J.J. Kallen, Juliette F. Bollemeijer, André C. Knulst, Anna M. Ehlers, Paco M.J. Welsing, Ronald van Ree, Thuy My Le
Clinical and Experimental Allergy, 2023, vol. 53, p.880-882

External positions

Member guideline committee immunotherapy

FrieslandCampina DSMB Project A.R.T.

Lectures for DBV

Member programme committee Hub Future Food Utrecht

Health council advice food allergy

member ILSI Europe expert group ‘Prioritisation of allergenic foods with respect to public health relevance’

chair guideline chronic urticaria

vice chair guideline food provocations

international advisory board chronic urticaria Novartis

Advisory board immunotherapy ALK-ABELLO

Giving lectures on allergic diseases for general practitioners, otolaryngologists (in training), pediatricians (in training), immunologist-allergologists (in training), dermatologists (in training), also on the European level