Alwin Huitema

Full Professor

Strategic program(s):

Contact

ahuitem8@umcutrecht.nl

Pure profile

Research groups

Clinical pharmacy research

Research aim

The mission of the clinical pharmacy program is to explain, predict and improve patients’ response to pharmacotherapeutic treatment using clinical pharmacological and clinical pharmacoepidemiological approaches.

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Recent publications

All publications

Unexpected Lack of Efficacy of Liposomal-Encapsulated Daunorubicin/Cytarabine in Pediatric FLT3 Wild-Type Newly Diagnosed AML Christian M Zwaan, Alwin Huitema
Journal of Clinical Oncology, 2026, vol. 44, p.2565-2568

Dosing challenges for chemotherapy and immunotherapy in congenital achondroplasia Karolijn W M Groot Beumer, E M J Durlinger, S W J Zielhuis, R Ter Heine, A D R Huitema, J J M A Hendrikx
Cancer chemotherapy and pharmacology, 2026, vol. 96

Population Pharmacokinetics of Bosutinib in Children with Philadelphia Chromosome-Positive Chronic Myelogenous Leukemia Based on a Phase I Dose-Finding Trial (ITCC-054/COG AAML1921) and Pediatric Recommended Phase II Dosage Evaluation Jen-Hao Wu, Francisco Bautista, Erica Brivio, Marieke Willemse, Karey Kowalski, Brian Jermain, May Garrett, Andrew Bukowinski, Carmelo Rizzari, Jessica Pollard, Laura Murillo-Sanjuán, Matthew Kutny, Sara Zarnegar-Lumley, Michele Redell, Stacy Cooper, Yves Bertrand, Arnaud Petit, Julie Krystal, Markus Metzler, Donna Lancaster, Jean-Pierre Bourquin, Jayashree Motwani, Inge M van der Sluis, Franco Locatelli, Michael E Roth, Nobuko Hijiya, C Michel Zwaan, Alwin D R Huitema
Clinical Pharmacokinetics, 2026, vol. 65, p.1389-1403

The impact of pazopanib and extremity radiotherapy on transaminase elevations in soft tissue sarcoma Bauke H G Van Riet, Shermarke Hassan, Thomas R De Wijkerslooth, Tom T P Seijkens, Alwin D R Huitema, Neeltje Steeghs, Rick L Haas
Acta oncologica (Stockholm, Sweden), 2026, vol. 65, p.641-651

Extrapolating Vincristine-Induced Peripheral Neuropathy From Caucasian to Kenyan Populations Maddalena Centanni, Mirjam Esther van de Velde, Alwin D R Huitema, Gertjan L Kaspers, Mats O Karlsson, Lena E Friberg
CPT: Pharmacometrics and Systems Pharmacology, 2026, vol. 15

The use of pharmacodynamic results for recommended phase II decision making in oncology clinical trials A C Kanhailal, M J J Lucassen, T Schutte, W Zwart, A D R Huitema, N Steeghs
Cancer chemotherapy and pharmacology, 2026, vol. 96

Fellowships & Awards

2015 Galenus research prize

2014 Huizinga penning of the Dutch Association of Hospital Pharmacists