Profile photo Alex Bhogal

Alex Bhogal

Assistant Professor

Strategic program(s):

Biography

I’m interested in vascular physiology and hemodynamics visualized using advanced MRI techniques combined with physiological stimuli. Also, i've grown a passion for metabolic imaging based in spectroscopy. My long term vision is to combine these incredible techniques to seach for a more complete picture of cerebral metabolism. I’m looking to collaborate on projects related to vascular reactivity, temporal aspects of the hemodynamic response in health and disease and the combination of multi-parametric data for tissue classification.

Research groups

Precision imaging

Research aim

Our research lines incorporate inventions of MR technology to be able to see the unseen for advancing medicine. Our clinical research focus areas are cancer, dementia, cardiovascular, stroke and MSK.

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Translational neuroimaging group

Research aim

To develop and apply advanced MRI methods for (pre)clinical research on neuronal and cerebrovascular biology in order to: 1) unravel critical aspects of brain impairment and recovery 2) advance brain treatments (focus: cerebrovascular diseases).

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Recent publications

Patterns of altered in vivo brain metabolism in patients with amyotrophic lateral sclerosis (ALS) and asymptomatic C9orf72 mutation carriers Henk Jan Westeneng, Abram D. Nitert, Kevin van Veenhuijzen, Carrie Wismans, Graziella Donatelli, Harold H.G. Tan, Wytse van Hoek, Michael A. van Es, Dennis W.J. Klomp, Alex A. Bhogal, Jan H. Veldink, Jannie P. Wijnen, Leonard H. van den Berg
EBioMedicine, 2025, vol. 121, p.1-18
Benefits and challenges of multi-delay arterial spin labeling in clinical practice Simone M Uniken Venema, Alex Bhogal, Jan Willem Dankbaar, H Bart van der Worp, Jeroen Hendrikse, Bart van der Zwan, Kees Braun, Jeroen C W Siero, Pieter T Deckers
Insights into Imaging, 2025, vol. 16
Small vessel dysfunction at 7T MRI locally predicts white matter damage progression in CADASIL Stanley Dt Pham, Hilde van den Brink, Anna Kopczak, Naomi Vlegels, Alberto De Luca, Benno Gesierich, Michael S Stringer, Michael J Thrippleton, Joanna M Wardlaw, Alex A Bhogal, Nikki Dieleman, Jacobus Jm Zwanenburg, Marco Duering, Geert Jan Biessels, Jeroen Cw Siero
Journal of Cerebral Blood Flow and Metabolism, 2025, vol. 46, p.521-533
Wand Julian P Merkofer, Dennis M J van de Sande, Sina Amirrajab, Kyung Min Nam, Ruud J G van Sloun, Alex A Bhogal
NMR in Biomedicine, 2025, vol. 38
A novel model to quantify blood transit time in cerebral arteries using ASL-based 4D magnetic resonance angiography with example clinical application in moyamoya disease Alex A. Bhogal, Simone M. Uniken Venema, Pieter T. Deckers, Kim van de Ven, Maarten Versluis, Kees P. Braun, Albert van der Zwan, Jeroen C.W. Siero
Journal of Cerebral Blood Flow and Metabolism, 2025, vol. 45, p.1069-1081
3D deuterium metabolic imaging (DMI) of the human liver at 7 T using low-rank and subspace model-based reconstruction Kyung Min Nam, Ayhan Gursan, Nam G. Lee, Dennis W.J. Klomp, Jannie P. Wijnen, Jeanine J. Prompers, Arjan D. Hendriks, Alex A. Bhogal
Magnetic Resonance in Medicine, 2024, vol. 93, p.1860-1873