A new study coordinated by researchers at UMC Utrecht and Amsterdam UMC shows that antibodies from Long COVID patients can induce persistent pain-like symptoms in mice. This provides evidence for a potential causal role of autoantibodies in Long Covid. These findings open the door to the development of targeted antibody-based therapies for Long COVID in the future.
Publication
Chen H-J, Appelman B, Willemen HLDM, Bos A, Prado J, Mak WA, Keijzer N, Silva Santos Ribeiro P, Vieira Goncalves S, Versteeg S, Geyer CE, Larsen M, Schüchner E, Bomers MK, Lavell AHA, Amsterdam UMC COVID-19 Biobank, Charlton B, Wüst R, Wiersinga WJ, van Vugt M, Vidarsson G, Eijkelkamp N, den Dunnen J. Transfer of IgG from Long COVID patients induces symptomatology in mice
