Neuroimmunology of Pain

Understanding how the interplay between the nervous system and immune system contributes to chronic pain development.

Our research

We focus on unraveling how interactions between the nervous system and the immune system drive the development of chronic pain. Building on these insights, we also investigate the neurological complications experienced by patients with post-infectious diseases. Our ultimate goal is to translate this knowledge into the discovery and development of urgently needed new (immune) therapeutics.

As a collaborative team, we aim to understand how pain normally resolves and how neuro-immune interactions contribute to chronic pain and neurological symptoms in post-acute infectious syndromes. Using these insights as building blocks, we strive to develop innovative therapies that improve lives for those suffering from these debilitating diseases.

Why It Matters

Chronic pain is more than discomfort: it is a disease with pandemic proportions.

  • 20% of the Western population suffers from chronic pain
  • 3 million people affected in the Netherlands alone
  • Numbers are rising due to aging, obesity, and post-infectious syndromes

The Treatment Gap

  • 80% of patients are dissatisfied with current pain management
  • Opioid-based therapies fuel addiction and the opioid crisis
  • Few effective, safe alternatives exist

The Urgent Need

Chronic pain is a growing global health challenge. We need innovative therapies that target the root causes, not just mask symptoms.

News

Hanneke on Dutch radio: Long COVID research remains a complex puzzle as symptoms differ greatly

7 november 2025 Read more

News item in Neuron: A less painful transfer of power

4 augustus 2025

Blog ZonMW: ‘Laten we kinderen niet vergeten in onderzoek naar de verstoorde afweer bij ME/CVS’

5 februari 2025

Utrecht University and UMC Utrecht awarded with fourteen NWO Vidi-grants

24 oktober 2024

Niels Eijkelkamp appointed as professor of Neuroimmunology of Pain

24 oktober 2024