Profile photo Pim van der Harst

Pim van der Harst

Full Professor

Strategic program(s):

Biography

I am an interventional cardiologist and scientist and head of the department of cardiology of the University Medical Center Utrecht. My clinical work includes the percutaneous treatment of obstructive coronary artery disease, including acute myocardial infarction. My translational research focusses on the analysis of big and complex data (e.g. genetic, ehr, imaging), including the use of machine learning and cloud computing, to improve our understanding and the early detection of coronary artery disease and heart failure. To this end we use large population based cohorts, including the Dutch PREVEND and LifeLine cohorts and the UK Biobank. Data on my "omics" research can be found our my website: www.cardiomics.net  In my clinical translational research I am also working on advanced image analysis, device interventions, machine learning, deep learning, and e/m Health to further improve and personalize care for our patients. Currently ongoing diagnostic imaging studies in include the REPLACE-IT (replacement of invasive coronary angiography) and the EARLY-SYNERGY (early detection of obstructive coronary artery disease; www.early-synergy.nl) studies. Currently interventional studies include the GIPS-IV, AXES and MRI-MC studies. Many of my projects based on collaborations with the most influential and creative individuals and research groups in the world.

Research groups

Inherited heart disease (cardiogenetics)

Research aim

We aim to enhance patient and family lives impacted by inherited cardiomyopathies. Our efforts target gene and variant identification, disease mechanisms, factors influencing disease outcomes, therapy optimization, and exploration of novel therapies.

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Recent publications

A genetic association study of circulating coagulation factor VIII and von Willebrand factor levels Paul S. de Vries, Paula Reventun, Michael R. Brown, Adam S. Heath, Jennifer E. Huffman, Ngoc Quynh Le, Allison Bebo, Jennifer A. Brody, Gerard Temprano-Sagrera, Laura M. Raffield, Ayse Bilge Ozel, Florian Thibord, Deepti Jain, Joshua P. Lewis, Benjamin A.T. Rodriguez, Nathan Pankratz, Kent D. Taylor, Ozren Polasek, Ming Huei Chen, Lisa R. Yanek, German D. Carrasquilla, Riccardo E. Marioni, Marcus E. Kleber, David Alexandre Trégouët, Jie Yao, Ruifang Li-Gao, Peter K. Joshi, Stella Trompet, Angel Martinez-Perez, Mohsen Ghanbari, Tom E. Howard, Alex P. Reiner, Marios Arvanitis, Kathleen A. Ryan, Traci M. Bartz, Igor Rudan, Nauder Faraday, Allan Linneberg, Lynette Ekunwe, Gail Davies, Graciela E. Delgado, Pierre Suchon, Xiuqing Guo, Frits R. Rosendaal, Lucija Klaric, Raymond Noordam, Frank van Rooij, Joanne E. Curran, Marsha M. Wheeler, Pim van der Harst, ,
Blood, 2024, vol. 143, p.1845-1855
Prognostic significance of echocardiographic deformation imaging in adult congenital heart disease Philippe J van Rosendael, Karim Taha, Marco Guglielmo, Arco J Teske, Pim van der Harst, Gertjan Sieswerda, Maarten J Cramer, Heleen B van der Zwaan
European Journal of Clinical Investigation, 2024, vol. 54
Healthcare consumption of patients with left ventricular assist device Lena Bosch, Peter-Paul M Zwetsloot, Maaike Brons, Gerardus P J van Hout, Manon G van der Meer, Mariusz K Szymanski, Anne-Marie Troost-Oppelaar, Faiz Z Ramjankhan, Pim van der Harst, Monica Gianoli, Marish I F J Oerlemans, Linda W van Laake
Netherlands Heart Journal, 2024, vol. 32, p.317-325
Equitable and specialised cardiovascular care in the Netherlands Pim van der Harst
Netherlands Heart Journal, 2024, vol. 32, p.303
Cost-utility analysis of TAVI compared with surgery in patients with severe aortic stenosis at low risk of surgical mortality in the Netherlands Rob Eerdekens, Suzanne Kats, Janneke P.C. Grutters, Michelle Green, Judith Shore, Pascal Candolfi, Wija Oortwijn, Pim Van Der Harst, Pim Tonino
Cost Effectiveness and Resource Allocation, 2024, vol. 22
ANOCA patients with and without coronary vasomotor dysfunction present with limited electrocardiographic remodeling Diantha J.M. Schipaanboord, Tijn P.J. Jansen, Caïa Crooijmans, N. Charlotte Onland-Moret, Suzette E. Elias-Smale, Aukelien C. Dimitriu-Leen, Pim van der Harst, Tim P. van de Hoef, René van Es, Peter Damman, Hester M. den Ruijter
IJC Heart and Vasculature, 2024, vol. 50

External positions

Editor-in-Chief - editor - bohn stafleu van loghum

Lid van de Raad van Toezicht - vele raakvlakken - Netherlands Heart Institute

begeleiden promovendi met afronden van hun promotie, eerste promotor - soortgelijk - Universitair Medisch Centrum Groningen

National member of Scientific Advisory Board LifeLines Cohort Study - ja, inhoudelijk advies - LifeLines B.V.

Nucleus member of the center for circulatory health at the UMC Utrecht - ja - UMC Utrecht

begeleiden promovendi met afronden van hun promotie, eerste promotor - soortgelijk - Universitair Medisch Centrum Groningen

National member of Scientific Advisory Board LifeLines Cohort Study - ja, inhoudelijk advies - LifeLines B.V.

Nucleus member of the center for circulatory health at the UMC Utrecht - ja - UMC Utrecht